Active Ingredient: The active ingredient present in Trexall is Methotrexate.

Drug Information: Methotrexate is the generic name for the trade drug, Trexall (Methotrexate) is an anti-cancer (cytotoxic) chemotherapy medicine. It is used for preventing Acute lymphoblastic leukemia (ALL), breast cancer, Non-Hodgkin’s lymphoma (NHL), Osteosarcoma and many other cancer forms.

How does Trexall work?

Methotrexate falls under the category of chemotherapy medications known as antimetabolites. Antimetabolites are very much alike to usual chemicals present within the cell. When the cells integrate these substances into the cellular metabolism, they are not capable to divide. Antimetabolites are cell-cycle specific. They hit these cells at very definite phases in the cycle. And result in cell death.

How to use Trexall?

The recommended dosage regimen of this medication will need to be individualized for each patient, and the major factor that the doctor will consider is the condition being treated.

What occurs if you miss a dose?

You can take the missed dose of Trexall the moment you remember. You may skip the missed dose if it is nearly the time for your subsequent planned dose. Avoid the intake of an added medicine to make up the missed dose.

Methotrexate is a strong medication. The dosage and how often you take this medication are based on your medical condition and response to treatment. There are many different dosing schedules for this medication (especially for cancer treatment). Therefore, it is very important that you follow your doctor’s instructions carefully. Take this medication by mouth as directed by your doctor.

For the treatment of psoriasis or rheumatoid arthritis, take this medication by mouthas directed by your doctor, usually once a week. It may take up to several months before you get the full benefit of this drug.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.

Drink plenty of fluids while taking this medication unless your doctor tells you otherwise. Doing so helps your kidneys to remove the drug from your body and avoid some of the side effects.


5mg 20 tablets, 7.5mg 30 tablets, 10mg 30 tablets, 15mg 30 tablets


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