What is ODOMZO?

ODOMZO  (sonidegib) is a prescription medicine used to treat adults with a type of skin cancer, called basal cell carcinoma, that has come back following surgery or radiation or that cannot be treated with surgery or radiation. It is not known if ODOMZO is safe and effective in children.

How should I take Odomzo?

Take Odomzo exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Take Odomzo on an empty stomach, at least 1 hour before or 2 hours after a meal.

You will need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results of these tests.

Store at room temperature away from moisture and heat.

Dosing information

Usual Adult Dose for Basal Cell Carcinoma:

200 mg orally once a day

Duration of therapy: Until disease progression or unacceptable toxicity

-This drug should be taken on an empty stomach at least 1 hour before or 2 hours after a meal.
-Prior to treatment initiation, serum creatinine kinase (CK) levels and renal function tests should be obtained from all patients, and the pregnancy status of females of reproductive potential should be verified.

Odomzo side effects

Get emergency medical help if you have signs of an allergic reaction to Odomzo: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Sonidegib can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have:

  • severe or unexplained muscle pain or weakness (even if this occurs after you have stopped taking this medicine);
  • little or no urinating; or
  • dark colored urine.

Common Odomzo side effects may include:

  • stomach pain, nausea, vomiting, diarrhea;
  • loss of appetite, weight loss;


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